A first of its kind observational study compares effectiveness of initial treatment choices for children and adolescents with multiple sclerosis — and finds an advantage for newer agents. Medscape Medical News
Inebilizumab is one of three new treatments for neuromyelitis optica — which have all shown striking degrees of efficacy — but are likely to be much more expensive than current mainstay therapy. Medscape Medical News
Satralizumab as monotherapy is effective vs placebo for reducing risk of relapses in patients with autoimmune neuromyelitis optica spectrum disorder (NMOSD), new research suggests. Medscape Medical News
The recurring question of whether to give MS patients vitamin D supplementation was the subject of one of the first ‘hot topics’ to be debated at the ECTRIMS meeting currently underway. Medscape Medical News
Primary progressive aphasia is associated with perturbations of connectivity within components of the brain’s language network, researchers report. Reuters Health Information
Although the primary outcome of a multinational phase 2 study was negative, researchers said promising secondary findings support the use of mesenchymal stem cells in patients with MS. Medscape Medical News
A neural prosthetic leg that restores sensory feedback can also improve walking performance and reduce phantom limb pain in above-knee amputees, a new proof-of-concept study suggests. Medscape Medical News
A Houston-area man who posed as a physician was found guilty of conspiring to unlawfully prescribe hundreds of thousands of doses of opioids at a "pill mill." Medscape Medical News
More evidence for using triptans alone or with NSAIDs for acute migraine and using a more holistic approach to prevention are highlights of pediatric guidelines updated for the first time since 2004. Medscape Medical News
Although cesarean deliveries have been linked previously with a higher risk for several disorders in offspring, new research also suggests an association with risk for autism and ADHD. Medscape Medical News
Challenging patients after a stroke with intense and complex tasks that mirror real-world challenges may improve walking skills such as gait symmetry, new research suggests. Medscape Medical News
Pooled data from two large trials points to a net benefit associated with 21 days of clopidogrel–aspirin therapy after a minor stroke or transient ischemic attack. Medscape Medical News
Preventing infections in patients with multiple sclerosis through routine immunizations is a key part of medical care, an updated practice guideline states. Medscape Medical News
Deaths from cardiometabolic causes continue to drop over time but are starting to plateau, a "concerning" development for the future, new research suggests. Medscape Medical News
Eculizumab is now indicated in Europe for adults with neuromyelitis optica spectrum disorder who are anti-aquaporin-4 (AQP4) antibody-positive and whose disease is following a relapsing course. International Approvals
Researchers make a strong play that multiple concussions in former football players are associated with a greater likelihood of lower testosterone levels and erectile dysfunction later in life. Medscape Medical News
Even small increases in blood pressure during an individual’s 30s and 40s are associated with white matter hyperintensities and lower brain volume in later life, new research suggests. Medscape Medical News
Oral istradefylline (Nourianz) reduces "off" episodes when added to levodopa/carbidopa in patients with Parkinson’s disease. FDA Approvals
Periodic limb movements in sleep with arousals are known to increase the risk for atrial fibrillation, but new research suggests they are also linked to increased risk for nonsustained ventricular tachycardia. Medscape Medical News
Tracking sNfL levels over time corresponds to multiple sclerosis disease course in a longitudinal study, but use of the blood biomarker for individual prognosis remains unclear. Medscape Medical News
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